Moore had been considered a favorite for her strong performance in “The Substance,” but Madison won for “Anora.”

Demi Moore snagged statuettes all through the awards season for her dynamic performance in “The Substance,” a film about the indignities women past 50 face in Hollywood. She was favored by many to win the Oscar for best actress.
But when the envelope was opened on Sunday night Moore, 62, was passed over in favor of Mikey Madison, 25, who pulled an upset and won the best actress trophy for playing a sex worker in the film “Anora.”
While Madison’s performance was widely praised, her unexpected victory left many admirers of Moore puzzled and saddened that it kept her from a perfect ending to her career comeback.
On social media and on a subreddit dedicated to Moore’s upset, some fans suggested that her loss underscored one of the central themes of the film: the challenges older actresses face in a Hollywood that is obsessed with young women.