It looks like Marquise “Hollywood” Brown won’t be the only notable name missing from the Kansas City Chiefs’ lineup after news came out on running back Clyde Edwards-Helaire.

The reigning Super Bowl champions open the 2024 NFL season on Thursday, and they will be without the running back after they placed him on the non-football illness (NFI) list, as ESPN reported, guaranteeing at least a four-game absence due to an apparent mental health issue.

The former LSU standout has been battling PTSD.

Clyde Edwards-Helaire opened up about his battle with the disorder last month, saying it began in December 2018 over what he described as a “self-defense situation.”

That matter caused him to miss time at training camp.

Edwards-Helaire said the disorder has caused him to vomit or not be in his profession mentally. He was diagnosed with post-traumatic stress disorder and is now on a treatment plan.

Chiefs RB Clyde Edwards-Helaire Reveals ‘Very Overwhelming’ Struggle With PTSD

Kansas City Chiefs running back Clyde Edwards-Helaire was absent from training camp practice for two days in July due to what the team referred to as an illness at the time.

The following Monday, Edwards-Helaire took to X — formerly Twitter — to explain what he’s dealing with.

“Living With PTSD is no small feat, it’s hard and very overwhelming,” Edwards-Helaire wrote. “Within the last month Ive Had many flare ups and the Amazing staff here at the #Chiefs have been helping me get through some tough times. I’ll be back rolling next Practice! All Love, Glydro.”

The 25-year-old did not elaborate further on what caused the post-traumatic stress disorder. It should be noted that he has been involved in two shootings since 2018.

Back in February 2024, Clyde Edwards-Helaire was declared a hero for shielding a child during a shooting at the Chiefs’ Super Bowl celebration.

In 2018, while still in college at LSU, he and a teammate were involved in a robbery gone wrong that resulted in the death of a man who was attempting to rob Edwards-Helaire and the teammate.